Sinead Delany-Moretlwe, MBBCh, PhD, DTM&H, is a Research Professor and Director: Research at the Reproductive Health and HIV Institute at the University of the Witwatersrand, Johannesburg. Her research interests span the intersections between sexual and reproductive health and infectious diseases, particularly in adolescent girls and young women. She has worked on several Phase III trials of new HIV prevention technologies, including oral, topical and, most recently, injectable PrEP. She has also led several studies to optimize oral PrEP use in adolescent girls and young women, as well as studies to evaluate HPV screening and vaccination approaches for populations living with HIV. She is currently an investigator on two studies evaluating new treatments and vaccines for gonorrhoea and is involved in several COVID-19 prevention trials. She is an advisor to the South African Department of Health PrEP technical working group and serves on several WHO and other advisory committees.