Melanie Ott, MD, PhD, is the Director and a senior investigator at the Gladstone Institute of Virology, a senior Vice President of Gladstone and a Professor of Medicine at UCSF. She studied under Nobel laureate Harald zur Hausen in Heidelberg, Germany, and has been recognized for her contributions to HIV cure research and the pathogenesis of hepatitis C and Zika virus infections. Since January 2020, she has pivoted part of her efforts to SARS-CoV-2 research. This work is focused on studying SARS-CoV-2 variants and harnessing the host response for new therapeutics using organoid technology. Her lab also develops new rapid diagnostics based on CRISPR and mobile phone technologies. She is the Program Director for the HOPE Collaboratory, a multidisciplinary group of researchers from around the world, and is an elected member of the Association of American Physicians (AAP) and a fellow of the American Academy of Microbiology (AAM).