Guten Morgen! We had a packed day yesterday with AIDS 2024 well and truly underway, including a special session on the strategies needed to overcome inequities.
You can hear from former New Zealand Prime Minister Helen Clark again today as she speaks during a plenary on addressing structural barriers. We also have groundbreaking science being shared – including news of the “next Berlin patient” – as well as the presentation of a host of IAS-supported prizes and awards. 07:00 CEST Satellite sessions get underway. 08:30 CEST Former New Zealand Prime Minister Helen Clark speaks on health as “a matter of global politics” at the plenary, “Addressing structural barriers: How can we do better?”. The session closes with the presenting of the Elizabeth Taylor Human Rights Award, supported by the IAS and Foundation for AIDS Research (amfAR). 10:30 CEST The AIDS 2024 Co-Chairs’ Choice special session features a presentation on the “next Berlin patient”, who sustained HIV remission for more than five years without antiretroviral therapy after a heterozygous CCR5 WT/Δ32 allogeneic hematopoietic stem cell transplant. Updated data will also be shared from the PURPOSE 1 Study on twice-yearly Lenacapavir or daily Emtricitabine/Tenofovir Alafenamide for HIV prevention in cisgender women. The session concludes with the awarding of the IAS President’s Award. 15:00 CEST You won’t want to miss “Reinvigorating parliamentary leadership in HIV”. Over 370 Members of Parliament from over 45 countries unite to put people first in rebuilding political support for ending HIV transmissions as part of the Global Parliamentary Platform on HIV and AIDS founding declaration. Today’s event features MPs from Argentina, Germany, United Kingdom and Zimbabwe and addresses the waning political commitment to the HIV response. Second-generation integrase strand transfer inhibitors (INSTIs) are first-line in all global and many national guidelines. The oral abstract session, “What if one-size INSTI doesn’t fit all?”, describes the impact of a one-size-fits-all strategy on national programmes, discusses access to alternative agents, and offers a clinical perspective on applying WHO guidelines to practice when access to monitoring is limited. Several sessions focus on keeping key populations at the centre: The oral abstract session, “TB or not TB?” updates on treatment for TB among people living with HIV. Explore a “tale of two diseases”, TB and hepatitis, with a focus on community-led monitoring and integrating self-testing into HIV and harm reduction services. 18:00 CEST Satellite sessions take place.
DoxyPrEP:
Yes,
you
read
that
correctly!
We’ve
known
about
doxycycline
post-exposure
prophylaxis
(DoxyPEP)
for
some
time.
Now
we
have
doxycycline
post-exposure
prophylaxis
(DoxyPrEP)
–
taking
the
antibiotic
before
sex.
Authors
of
two
small
studies
from
opposite
sides
of
the
world
presented
findings
yesterday.
A
trial
from
Canada
involving
men
who
have
sex
with
men,
living
with
HIV
and
with
a
history
of
syphilis,
showed
reductions
of
79%
in
syphilis,
92%
in
chlamydia
and
68%
in
gonorrhoea
in
the
doxycycline
arm
compared
with
the
placebo
arm.
A
study
from
Japan
among
female
sex
workers
showed
a
drop
in
STI
incidence
from
232.3
to
79.2
per
100
person-years.
Syphilis
incidence
was
zero
and
chlamydia
incidence
reduced
significantly.
According
to
the
study
team,
the
findings
support
introduction
of
DoxyPrEP
in
populations
that
are
highly
vulnerable
to
STIs.
DoxyPEP:
STI
rates
among
young
women
using
PrEP
in
central,
eastern,
southern
and
western
Africa
are
high.
Trials
here
show
that
DoxyPEP
effectively
prevents
STIs
among
cisgender
men
and
trans
women
but
not
cisgender
women
because
use
of
DoxyPEP
is
low,
with
barriers
such
as
side
effects,
pill
burden,
stigma
and
fear
of
partner
reaction.
A
study
on
DoxyPEP
adherence
among
young
women
in
Kenya
showed
that
adherence
could
be
better
supported
by
decreasing
frequency
and
urgency
dosing
to
allow
for
optimal
location
and
timing
of
dosing.
Reaching
the
targets:
The
odds
of
people
living
with
HIV
knowing
their
HIV
status
increases
by
a
factor
of
almost
2
in
countries
that
have
adopted
civil
society
freedom
policies.
A
legal
and
policy
review
for
194
countries
from
2017
to
2023
concluded
that
legislation
and
freedom
policies
for
civil
society
have
an
impact
on
national
ability
to
reach
AIDS
targets.
“The
adoption
of
national
laws
supporting
both
CSO
[civil
society
organization]
operational
freedom
and
social
contracting
should
be
a
priority
for
the
global
AIDS
response,”
the
researchers
say.
Preparing
for
the
next
pandemic:
How
can
lessons
from
COVID-19
and
HIV inform
preparedness
for
“Disease
X”,
a
theoretical
future
pandemic?
A
grey
literature
review
on
the
HIV
and
SARS-CoV-2
responses
identified
tactics
used
by
civil
society,
governments
and
global
actors
that
could
be
pivotal
in
Disease
X
response.
Many
lessons
from
HIV
were
not
taken
up
in
COVID-19
and
must
be
in
future
pandemics,
the
researchers
concluded.
Foremost
is
addressing
inequality,
using
a
global
public
goods
approach
and
mobilizing
communities,
with
policies
and
programmes
improving
vulnerable
people’s
social
and
economic
conditions.
Towards
equity:
Inequity
still
drives
the
HIV
pandemic
and
is
a
great
barrier
to
ending
HIV
as
a
public
health
threat.
The
special
session,
“Inequities
forever?”,
emphasized
the
need
for
global,
regional
and
national
strategies
that
go
beyond
public
health
interventions
to
address
structural
inequalities.
The
symposium,
“Equity
in
focus:
Tackling
inequalities”,
dissected
such
challenges
as
criminalization
of
key
populations;
medical
torture,
loss
of
dignity
and
forced
testing;
gender
inequality;
and
access
to
testing
and
treatment.
It
also
highlighted
the
vital
role
of
community-led
organizations
in
addressing
challenges.
Health
and
human
rights:
Members
of
the
International
AIDS
Society–Lancet
Commission
on
Health
and
Human
Rights
shared
findings
and
recommendations.
The
commission
described
the
COVID-19
pandemic
as
“a
failed
test
case
for
the
world’s
commitment
to
international
solidarity,
equity,
and
human
rights”
and
climate
change
as
“already
having
severe
health
and
economic
consequences
in
the
communities
and
societies
least
responsible
for
it”.
Find
its
full
report
here.
Here are some picks around the theme of healthcare and treatment: - “SExT: Sex Education by Theatre” is an award-winning, trauma-informed peer education programme from Canada. It makes its international debut in the Global Village at 14:00 CEST!
- “The face of care” showcases the experiences and challenges of frontline providers in the paediatric-adolescent HIV response on the African continent.
- “Into chems?” is an open space to talk about chemsex and other sexualized psychoactive substance use practices and coordinated local, regional and global responses.
- This workshop at 11:00 CEST shares approaches, resources and learning from the UK Fast-Track Cities, London and Bristol, for reducing internalized stigma for people living with HIV and educating healthcare providers about HIV to reduce stigma in healthcare settings.
- More broadly, share your thoughts on restoring political momentum towards ending the HIV pandemic. At 16:30 CEST, join the dialogue between communities, civil society and parliamentarians at the GFAN and APH Ukraine Networking Zone.
Listen to the latest episode of HIV unmuted, the award-winning IAS podcast, on the game-changing research from AIDS 2024, the 25th International AIDS Conference. Sharon Lewin, the IAS President and AIDS 2024 International Co-Chair, sits down with our new host, Juan Michael Porter II. They delve into a broad range of exciting science, from long-acting injectables to new research on doxycycline prophylaxis to advances in cure research, including the “next Berlin Patient”.
The
rapporteur
summaries
are
your
go-to
resources
for
the
highlights
presented
at
AIDS
2024.
Thanks
to
the
AIDS
2024
team
of
experts,
delegates
can
access
daily
recaps
by
each
programme
track here.
Among posters on display today are: - The Pilot SMART trial of motivational enhancement interventions to increase PrEP use in sexual minority men
- Advancing human rights to break the cycle of violence against people who inject drugs and trans people in the DRC
- Host metabolites that modulate the efficacy of romidepsin in reactivating latent HIV
- A look at “myHIV forum” and the importance of an online platform for people living with HIV
- How an integrated HIV/HTN care model improves individual-level blood pressure reduction among adults with HIV in Uganda
- Insights into psychosocial influences on men who have sex with men and their use of PrEP
JIAS
supplement
just
launched
Just published! Read all oral abstracts from AIDS 2024 in the new Journal of the International AIDS Society abstract supplement. Tune in to the AIDS 2024 Live Show at 08:30 CEST daily to learn about conference developments and what lies ahead. Host Karl Schmid will be live from the Global Village and joined by leading voices in the HIV response. Today's scheduled guests include: - Glory Alexander, ASHA Foundation
- Rahul Kumawat, Positive YUVA Network
- Joyce Ouma, Y+ Global
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