Global Fellows Research Academy
Institution: Noguchi Memorial Institute for Medical Research, University of Ghana
Country of work: Ghana
What is your motivation for engaging in HIV cure and remission research?
In my estimation, the ultimate goal of all HIV research is to find a cure. Thus, no matter how well scientists understand HIV and even develop an effective vaccine against it; we will only be seen as scratching the surface until the day we discover an HIV cure. Therefore, I have a keen interest in conducting research that will contribute knowledge to and data towards efforts at finding an HIV cure.
What is your current area of research?
My current research project is investigating the interplay of APOBEC3G/F-expression and polymorphisms in the HIV-1 vif gene of elite controllers and long term non-progressors to understand how these factors contribute to the control of HIV replication and disease progression. This is imperative since understanding viral-host interactions will provide data towards finding HIV cure or remission. I am also interested in understanding viral persistence during antiretroviral therapy and the role of latently infected cells.