Poster Exhibition
The abstracts presented at the 2019 HIV & HBV Cure Forum are published in a supplement of the Journal of Virus Eradication and can be found in the abstract portal here.
All photos from the forum can be accessed here.
P1: Reduced immune activation and low inflammatory monocyte frequencies during pregnancy are associated with preterm delivery
N. Mdletshe, C. Thobakgale, T. Malaba, L. Myer, C. Gray, M. Altfeld, M.-L. Newell, T. Ndung’u, Prematurity Immunology and HIV-infected mothers and their infants Study (PIMS)
South Africa
Poster available soon
P2: Phenotype and functionality of CD8+ T-cells before and after cART are related to the viral reservoir size in HIV infected subjects
Czernikier, J. Salido, C. Trifone, M.I. Figueroa, H. Salomón, P. Cahn, O. Sued, N. Laufer, Y. Ghiglione, G. Turk
Argentina
Poster available soon
P3: Early skewed differentiation and PD-1 expression in CD4+ T-cells relate to immune dysfunction and viral persistence in HIV+subjects one year post-cART initiation
J. Salido, A. Czernikier, C. Trifone, M.I. Figueroa, H. Salomón, P. Cahn, O. Sued, N. Laufer, Y. Ghiglione, G. Turk
Argentina
Poster available soon
P4: Nef genotype influences immune control in HIV-1 infected individuals carrying protective alleles
F. Method Mwimanzi, I. Ngare, M. Mori, J. Mann, P. Goulder, T. Ndung'u, T. Ueno
Japan
Poster available soon
P5: CD4+ T-cells expressing negative checkpoint receptors are associated with decreased mitochondrial oxidative phosphorylation in chronic HIV
L.M. Gangcuangco, C. Shikuma, B. Mitchell, S. Bowler, G. Chew, L. Ndhlovu, K. Kallianpur, M. Gerschenson, S. Souza, D. Chow
Philippines
Poster available soon
P6: Immune Activation Is Associated With Poor CD4 Reconstitution - A Study from South India
S. Saravanan, B. Kausalya, T. Dinesha, J. Boobalan, S. Sivamalar, S. Gomathi, A. Pradeep, S. Solomon, D. Smith, K. Murugavel
India
Poster available soon
P7: Relevance of Reg3α and I-FABP on microbial translocation, inflammation and reservoir size in people living with HIV
S. Isnard, R. Ramendra, F.P. Dupuy, V. Mehraj, J. Lin, N. Kokinov, B. Lebouché, C. Costiniuk, P. Ancuta, N.F. Bernard, M. Durand, C. Tremblay, J.-P. Routy, Montréal Primary HIV-infection study group, Canadian HIV and Aging cohort, and Canadian HIV infected slow progressors study
Canada
Poster available soon
P8: Persistent elevation of Tim-3 and PD-1 on memory T cells despite early ART initiation during primary HIV infection
G.E. Martin, M. Pace, J. Meyerowitz, J.P. Thornhill, J. Lwanga, H. Lewis, T. Solano, R. Bull, J. Fox, N. Nwokolo, S. Fidler, C.B. Willberg, J. Frater, CHERUB investigators
United Kingdom
Poster available soon
P9: Extracellular vesicles and their microRNA contents are biomarkers of HIV-1 disease progression
W.W. Bazié, J. Vitry, J. Boucher, E. Côté, S. Trottier, C. Gilbert
Burkina Faso
Poster available soon
P10: Tissue-specific effects of latency reversing agents on HIV transcriptional blocks in gut & blood
S. Telwatte, P. Kim, T.-H. Chen, J. Milush1, M. Somsouk, P. Hunt, S. Deeks, J. Wong, S. Yukl
United States
Poster available soon
P11: Different HIV Transcriptional Profiles in Memory CD4+ T Cells Subsets during ART
M.J. Ruiz, J. Plantin, A. Pagliuzza, M. Massanella, R. Fromentin, J.-P. Routy, N. Chomont
Canada
Poster available soon
P12: In-depth transcription profile comparison of multiple primary cell HIV latency models
S. Moron-Lopez, I. Sarabia, E. Battivelli, M. Montano, S. Telwatte, A. Bosque, E. Verdin, W. Greene, J.K. Wong, S.A. Yukl
United States
Poster available soon
P13: Hormonal control of HIV-1 latency by estrogen imparts gender-specific restrictions on the latent reservoir
J. Karn, C. Dobrowolski, S. Valadkhan, P. Wille, R. Hoh, M. Ghandi, S. Deeks, E. Scully
United States
Poster available soon
P14: Cell-associated HIV RNA and the ratio of HIV RNA to DNA have circadian cycles in HIV-positive individuals on antiretoviral therapy
J. Stern, M. Roche, A. Solomon, A. Dantanarayana, A. Reynaldi, M. Davenport, S.G. Deeks, W. Hartogenesis, F.M. Hecht, L. Cockerham, S.R. Lewin
Australia
Poster available soon
P15: Cellular modulation and HIV reactivation in response to serial treatment of latently HIV infected CD4 T cells with Histone Deacetylase inhibitors (HDACi)
J. Maxwell, A. Nefedov, C. Dorfmeier, G. Wu, Y. Li, P. Zuck, D. Hazuda, A. Webber, R. Barnard, B. Howell
United States
Poster available soon
P16: Galectin-1 promotes HIV-1 latency reactivation
J. Rubione, G. Duette, P. Perez, P. Pereyra Gerber, J. Salido, A. Cagnoni, L. Guzman, A. Adamczyk, O. Sued, Y. Ghiglione, N. Laufer, K. Mariño, G. Rabinovich, M. Ostrowski
Argentina
Poster available soon
P17: Cellular proliferation maintains genetically intact and defective HIV-1 over time
B Horsburgh, B. Hiener, J.-S. Eden, E. Lee, T. Schlub, S. von Stockenstrom, L. Odevall, J. Milush, T. Liegler, R. Hoh, R. Fromentin, N. Chomont, S. Deeks, F. Hecht, S. Palmer
Australia
Poster available soon
P18: The CARMA study - children on early suppressive therapy: total HIV-1 DNA quantitation 12 years post ART initiation
C. Foster, S. Dominguez, A. Tagarro, E. Nastouli, P. Palma, R. Gkouleli, J. Heaney, C. Giaquinto, P. Rossi, P. Rojo, EPIICAL
Spain
P19: CD32+CD4+ T cells are highly enriched in HIV DNA
A.Pasternak, G. Darcis, N. Kootstra, B. Hooibrink, T. van Montfort, K. Groen, S. Jurriaans, M. Bakker, C. van Lint, B. Berkhout
The Netherlands
Poster available soon
P20: Kansui, an Ingenol-Containing Herbal Supplement, Safely Induced CD8, NK, and Monocyte Activation in Three ART-Suppressed SIVmac251-Infected Rhesus Macaques
S. Lee, K. Kesmy, P. Bacchetti, R. Hoh, J. Lifson, D. Cary, B. Peterlin, S. Deeks, D. Hartigan-O'Connor
United States
Poster available soon
P21: Large in vivo expansion and subsequent partial contraction of a T-cell clone carrying a defective HIV genome reflect the dynamics of the HIV reservoir during ART
R. Fromentin, M. Massanella, C. Vandergeeten, V. Morcilla, W.W. Chiu, D. Looney, M. Ramgopal, D.D. Richman, L. Trautmann, S. Palmer, N. Chomont
Canada
Poster available soon
P22: Different regimens of Romidepsin administration for reversion of SIV latency in a rhesus macaque model of complete virus control
A. Kleinman, S. Murali Kilapandal Venkatraman, E. Penn, B. Policicchio, P. Sette, E. Brocca-Cofano, M. Cottrell, R. Sivanandham, A. Valentine, C. Xu, K. Raehtz, T. Dunsmore, G. Haret-Richter, A. Kashuba, J. Mellors, I. Pandrea, C. Apetrei
United States
Poster available soon
P23: Human Endogenous Retrovirus expression landscape in models of HIV-1 latency
M. de Mulder Rougvie, G. Beckerle, M. Bendall, L.P. Iniguez, D. Nixon
United States
Poster available soon
P24: The SMAC mimetic AZD5582 reverses HIV latency as a single agent in resting primary CD4+ T Cells
G. Sampey, D. Irlbeck, E. Browne, M. Kanke, E. Cule, S. Wills, S. Falcinelli, Z. Wang, J. Kircherr, B. Allard, E. Stuelke, K. Sholtis, R. Ferris, J. Brehm, D. Favre, J.-P. Routy, C. Jones, N. Archin, D. Margolis, R. Dunham
United States
Poster available soon
P25: Development of Cytotoxic Enhancing Agents (CEAs) to improve Shock-and-Kill strategies
T. Zaikos, R. Durga, S.-H. Huang, R. Brad Jones, A. Bosque
United States
Poster available soon
P26: Sting agonist as a kick and kill agent to target the HIV reservoir
M. Mavigner, A.D. Brooks, A. Koblansky, C. Galardi, H. Madsen, D.M. Margolis, G. Silvestri, A. Chahroudi
United States
Poster available soon
P27: CD8 depletion plus signalling of the non-canonical NF-kB pathway reverses latency in SIV-infected, ART-suppressed rhesus macaques
M. Mavigner, A.D. Brooks, G.K. Tharp, C. Mattingly, N. Schoof, T.H. Vanderford, S.E. Bosinger, G.C. Sampey, C. Galardi, R.M. Dunham, D.M. Margolis, G. Silvestri, A. Chahroudi
United States
Poster available soon
P28: Discovery and mechanistic study of novel suppressors of post-integrated HIV expression from African natural products
C. Schonhofer, K. Andrae-Marobela, J. Yi1, A. Cochrane, A. Pagliuzza, B. Abegaz, R. Davis, N. Chomont, Z. Brumme, M. Brockman, I. Tietjen
Canada
P29: Sustained SHIV reactivation by N-803 in ART-treated CD8-depleted macaques
J.B. McBrien, D.G. Carnathan, E. White, J. Lifson, J.H. Lee, J.T. Safrit, M. Paiardini, A. Chahroudi, G. Silvestri
United States
Poster available soon
P30: Latency reactivating agents : impact on human macrophages physiology and susceptibility to HIV-1 infection
L. Hany, M.-O. Turmel, C. Barat, M. Ouellet, M.J. Tremblay
Canada
Poster available soon
P31: Lessons from the Research in Viral Eradication of Reservoirs (RIVER) study: impact of a therapeutic vaccine targeting conserved HIV epitopes on T cell function in treated primary infection
J. Kopycinski, H. Yang, E. Kim, W. Stohr, T. Hanke, J. Frater, S. Fidler, L. Dorrell, RIVER trial investigators
United Kingdom
Poster available soon
P32: Oral TLR7 Agonist Administration Induces an Immunostimulatory Response in SIV-Infected ART-Suppressed Infant Rhesus Macaques
K. Bricker, V. Obregon-Perko, J. Hesselgesser, A. Chahroudi
United States
Poster available soon
P33: Allogeneic Stem Cell Transplant in HIV-1 Infected Individuals; An update of the IciStem Consortium
A.M.J. Wensing, M. Salgado, M. Kwon, J.M. Eberhard, A. Saez-Cirion, J. Schulze zur Wiesch, G. Hütter, J. Badiola-González, A. Bandera, L. Barrett, R.K. Gupta, B.E. Jensen, J.H.E. Kuball, L. Martín Carbonero, M. Nabergoj, K. Raj, R. Saldaña-Moreno, G. Scarlatti, L. Vandekerckhove, J.L. Díez Martín, M. Nijhuis, J. Martínez-Picado, IciStem Consortium
The Netherlands
Poster available soon
P34: CRISPR/Cas9 targeting HIV-1 regulatory genes inactivates latent proviral DNA and prevents new infection in T cell culture with inhibition of viral escape
Y. Ophinni, M. Inoue, T. Kotaki, M. Kameoka, Y. Hayashi
Japan
Poster available soon
P35: Rapamycin immune tolerization enables gene transfer following subcutaneous delivery of AAV6 but not CD4-retargeted AAV6 vectors in AAV-seropositive rhesus macaques
K. Jerome, D. Stone, E. Kenkel, M. Tanaka, S. Wangari, J. Ahrens, H.D. Feelixge, A. Kumar, W. Obenza, C. Peterson, H.-P. Kiem, L. Stensland, R. Mumane, M.-L. Huang, M. Aubert, S.-L. Hu
United States
Poster available soon
P36: Preferential infection of α4β7+ CD4+ T cells in early acute HIV-1 infection
L. McKinnon, A. Tokarev, A. Pagliuzza, A. Sivro, E. Kroon, N. Chomchey, N. Phanuphak, A. Schuetz, M. Robb, J. Ananworanich, N. Chomont, D. Bolton, on behalf of the RV254/SEARCH010 study
Canada
Poster available soon
P37: High HIV viral burden persists in CXCR3+Tfh despite very early cART initiation
O. Baiyegunhi, J. Mann, T. Nkosi, J. Pansegrou, K. Dong, T. Ndungu, B. Walker, Z. Ndhlovu
South Africa
Poster available soon
P38: Immune-phenotypic characteristics associated with an effective acute-phase response predict a reduced amount of integrated HIV DNA in naïve CD4+ T-cells in patients treated during acute HIV infection
A. Camiro-Zuñiga, M.A. Najera-Avila, M.D.R. Jaramillo-Jante, L. Gibellini, S. De Biasi, M. Pinti, E. Bianchini, D. Lo Tartaro, A. Neroni, M. Nasi, C. Mussini, L.E. Soto-Ramírez, J.J. Calva, P.F. Belaunzarán-Zamudio, B. Crabtree-Ramirez, J.G. Sierra-Madero, C. Hernández-Leon4, J.L. Mosqueda-Gómez, S. Navarro-Álvarez, D. Scott-Algara, A. Cossarizza, S. Perez-Patrigeon
Mexico
Poster available soon
P39: HIV infection of hepatitis B virus (HBV)-infected hepatocytes increases CXCL10 production and is associated with liver fibrosis in HIV-HBV co-infected individuals
K.P. Singh, J.M. Zerbato, W. Zhao, S. Braat, C. Deleage, S. Tennakoon, H. Mason, A. Rhodes, A. Dantanarayana, A.N. Harman, J. Rhodes, J. Torresi, P. Revill, J. Estes, A. Avihingsanon, S.R. Lewin, J. Audsley
Australia
Poster available soon
P40: Hepatitis B Virus co-infection in Panama, evaluation of prevalence and factors associated with new HIV infections, period 2016-2017
J. Góndola, J. Castillo, O. Castillero, C. González, A. Moreno, O. Chavarría, A. Ortíz, J.M. Pascale, A. Martínez
Panama
Poster available soon
P41: Diagnostic of HIV, TB and Hepatitis using GeneXpert platform in Africa: challenges, lessons learnt and way forward in the era of the Sustainable Development Goal
J.D.D. Iragena, F. Jallow, F. Mosha, H. Lago
Congo
Poster available soon
P42: Inflammatory markers associated with mortality in HIV-positive individuals from Côte d’Ivoire: role of HIV-HBV co-infection
G.M. Kouame, A. Boyd, R. Affi, R. Moh, A. Badjé, D. Gabillard, J.-B. N'takpé, S.-P. Eholié, K. Lacombe, A. Inwoley, X. Anglaret, C. Danel, the ANRS 12136 Temprano study
Côte d'Ivoire
Poster available soon
P43: Efficacy and safety of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide as maintenance treatment of patients with HIV and HBV coinfection
Y.-S. Huang, C.-Y. Cheng, H.-Y. Sun, P.-L. Lu, C.-H. Lee, S.-H. Cheng, Y.-T. Lee, B.-H. Liou, C.-E. Liu, C.-J. Yang, H.-J. Tang, S.-P. Lin, M.-W. Ho, S.-H. Huang, H.-C. Tsai, C.-C. Hung, Taiwan HIV Study Group
China
Poster available soon
P44: No evidence of neuroaxonal injury following latency reversal with vorinostat and HIV-1 specific vaccination in the RIVER trial
J. Alagaratnam, W. Stohr, J. Toombes, H. Zetterberg, S. Pett, M. Nelson, S. Kinloch, A. Clarke, N. Nwokolo, M. Johnson, J. Fox, T. Hanke, J. Kopycinski, L. Dorrell, A. Babiker, J. Frater, A. Winston, S. Fidler, RIVER trial investigators
United Kingdom
Poster available soon
P45: The impact of vorinostat and AGS-004, a dendritic cell-based immunotherapy, on persistent HIV-1 Infection
C. Gay, J.D. Kuruc, S.D. Falcinelli, J. Warren, J.L. Kirchherr1, K. Sholtis, B. Allard, E. Stuelke, A. Gamble, A. Plachco, I. Tcherapanova, J.J. Eron, N. Goonetilleke, M. DeBenedette, C.A. Nicolette, N.M. Archin, D.M. Margolis
United States
Poster available soon
P46: How Do HIV Cure Trial Researchers Respond to an Embedded Social Science Study?
H. Peay, S. Isaacson, N. Ormsby, A. Corneli, R.J. Cadigan, G. Henderson
United States
Poster available soon
P47: Barriers and facilitators of open contests to promote community engagement in HIV cure research: a qualitative evaluation among trial participants and community members
Y. Zhao, H. Bao, S. Day, L. Li, A. Mathews, J.D. Tucker
United States
Poster available soon
P48: Transgender women’s perceptions of HIV cure research: Qualitative interviews with transgender women living with HIV in Baltimore, MD, United States
T. Poteat, K. Dubé, A. Aqil, D. Evans
United States
Poster available soon
P49: Patient perspectives of HIV cure
K. MacDonald, S. Gupta, M. Ott, G. Zimet
United States
Poster available soon
P50: How will eventual HIV cure impact prevention behavior?
M. Magnus, J. Kanyinda, C.A. Boone, T. Young, E. Sarkodie, R. Strange, N. Caballero-Suarez, J. Fenech, T. Villa, A. Castel
United States
Poster available soon