5th HIV-Exposed Uninfected Child and Adolescent Workshop

21 July 2019 | Mexico City, Mexico

In high-HIV burden countries where pregnant and breastfeeding women living with HIV are receiving antiretroviral treatment, up to 30% of children are now HIV exposed and uninfected but not HIV unaffected as HEU children experience poorer outcomes than their unexposed peers.

The HIV-Exposed Uninfected (HEU) Child and Adolescent Workshop provides the only international annual forum for dialogue and discussion among the community of clinicians, scientists, epidemiologists, public health and policy experts, families living with HIV and advocates concerned about the short-, medium- and long-term well-being of HEU children and adolescents.

Previous workshops have considered immunological and infectious disease vulnerability in HEU infants, methodologic challenges to studying this population, potential consequences of in utero and early exposure to antiretroviral drugs and how to study these. They have also looked at early childhood development and psychosocial implications for HEU adolescents. The 5th workshop will be a full-day pre-meeting event that includes sessions on the first 1,000 days for HEU children, with focus on the in utero environment through to the postnatal environmental and infant feeding exposures up to the age of two years. Panel discussions will explore how to partner for progress in ensuring that all children, including HEU children, survive and thrive.

Download the programme

Meeting material

  • Photos & Video
  • Presentations

Session 1: The First 1000 days for children who are HIV-Exposed and Uninfected (CHEU) – Part 1

Overview of the population of children who are HEU
Amy Slogrove (Stellenbosch University)


The impact of maternal HIV infection on placental and neonatal immunology among CHEU
Clive Gray (University of Cape Town)


ARV exposure and placental morphology/function
Lena Serghides (University of Toronto)


Maternal determinants of immunity among CHEU
Arnaud Marchant (Université Libre de Bruxelles)

Presentation unavailable for download

Child mortality, growth and early childhood development – comparing children who are CHEU and children without HIV exposure in the SHINE Trial
Ceri Evans (Queen Mary University London, ZVITAMBO Institute)


Infant feeding and WASH interventions among CHEU in SHINE
Andy Prendergast (Queen Mary University London, ZVITAMBO Institute)


Session 2: The First 1000 days for CHEU: Part 2

Follow-up of CHEU through routine child health services: the Zambian perspective
Priscilla Mulenga (Zambian MoH) and Jane Mutanga (Livingstone Central Hospital)


Providing care for CHEU through routine child health services: the South African perspective
Lesley Bamford (SA NDoH) and Ute Feucht (University of Pretoria)


Policy updates – integrating CHEU into the Nurturing Care Framework
Martina Penazzato (World Health Organization)


Session concluding remarks
Claire Thorne (University College London)


Session 3: Optional session - Harmonization and Collaboration for scientific advancement

Harmonizing CHEU Exposure and Outcome Data – The INFORM Project
Kate Powis (Massachusetts General Hospital for Children)


The DECIPHER Project – Towards consensus on HIV and ARV exposure definitions
Barbara Burmen (University of Cape Town)


Past workshops materials and reports

3rd HEU Workshop - 2017: report, presentation slides and pictures
4th HEU Workshop - 2018: presentation slides, video and pictures

Organizing committee

Amy Slogrove, Stellenbosch University, South Africa
Kate Powis, Harvard University, United States
Ute Feucht, University of Pretoria, South Africa
Tessa Goetghebuer, CHU Saint-Pierre, Belgium
Martina Penazzato, WHO, Switzerland
Shaffiq Essajee, UNICEF, United States
George Seage III, Harvard University, PHACS, United States
Rohan Hazra, National Institutes of Health, United States
Marissa Vicari, International AIDS Society, Switzerland
Daphnée Blanc, International AIDS Society, Switzerland

For any question on the workshop please contact [email protected]

In collaboration with:

1st International Paediatric HIV Symposium in Africa - Virtual Symposium 17-18 November 2021




Annual Impact Report 2020

CIPHER Grant Programme
Awards up to $150,000 to early-stage investigators to address critical research gaps in paediatric and adolescent HIV in resource-limited settings.

CIPHER Growing the Leaders of Tomorrow Fellowship
Provides support to young investigators in sub-Saharan Africa on priority research topics in paediatric and adolescent HIV clinical science.

CIPHER Global Cohort Collaboration
Brings together the largest collaboration of paediatric and adolescent HIV observational cohort networks to answer key questions of global public health.

Research agendas for paediatric and adolescent HIV