International AIDS Society
International AIDS Society
 
 
   

“TOWARDS AN HIV CURE”: AIDS 2012 PRE-CONFERENCE SYMPOSIUM
20 & 21 JULY 2012



Background

Under the auspices of the International AIDS Society, an international working group of researchers developed a Global Scientific Strategy aimed at building a global consensus on the state of the HIV reservoirs field and defining scientific priorities that must be addressed by future research to tackle HIV persistence in patients on antiretroviral therapy.

The Global Scientific Strategy: Towards an HIV Cure was released at a 2-day symposium, co-chaired by Françoise Barré-Sinoussi, 2008 Nobel Laureate for Medicine and IAS President-elect and Steven Deeks, Professor of Medicine at the University of California, San Francisco (UCSF) for up to 250 basic and clinical science researchers and research advocates. The symposium took place in Washington, D.C. on 20 & 21 July 2012, immediately preceding the XIX International AIDS Conference.


Objectives
  • Develop knowledge on the priorities that future research must address in order to tackle HIV persistence in patients on ART.
     
  • Accelerate research on viral reservoirs as the way towards achieving a cure for HIV infection
     
  • Provide an opportunity for scientists who are working on HIV cure to share ideas, debate, and network among their peers
     
  • Promote better investments in HIV/AIDS cure research

Themes of the symposium; presentations & abstracts

The symposium was structured around an opening keynote speaker, 7 thematic sessions including invited presentations and abstract presentations, a closing keynote presentation and a poster exhibition.

The themes of the symposium were:

Day 1
  • Cellular and viral mechanisms that maintain HIV persistence
  • Tissue and cellular sources of persistent HIV in long-term ART-treated individuals
  • Origins of immune activation and inflammation in the presence of ART and their consequences for HIV persistence
Day 2
  • Host and immune mechanisms that control infection but allow viral persistence
  • Assays to measure persistent infection: comparison and validation
  • Therapeutic agents or immunological strategies to safely eliminate latent infection in individuals on ART
  • Strategies to enhance the capacity of the host response to control active viral replication

Details of the symposium

The symposium was closely linked to the AIDS 2012 conference programme. Track A and B (basic and clinical sciences) abstracts submitted to the International AIDS Conference and related to the topic of HIV cure were considered for the symposium (oral presentations and posters), while results from the symposium were shared with the participants attending AIDS 2012.

Please click here for more detailed information on the background and objectives of this initiative and for any additional information please contact .


Continuing Medical Education (CME) Accreditation

The University of California, San Francisco School of Medicine (USCF) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

UCSF designates this live activity for a maximum of 13 AMA PRA Category 1CreditsTM.

This activity has been planned and implemented in accordance with the essential areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the University of California, San Francisco School of Medicine (UCSF) and International AIDS Society.


IAS-ANRS Prize on HIV Cure

The US$2,000 IAS/ANRS Young Investigator Award is jointly funded by the IAS and the Agence Nationale de Recherche sur le sida et les hépatites virales (ANRS) to support young researchers who demonstrate innovation, originality, rationale and quality in the field of HIV/AIDS research.


Nitasha Kumar, Alfred Monash University and Burnet Institute, Australia received the 2012 IAS-ANRS Young Investigator Award for HIV Cure for her research on myeloid dendritic cells and HIV latency in resting T cells in Sharon Lewin's laboratory.


The Symposium Programme Committee

 

 
AIDS 2012 Affiliated Independent Event

Online Symposium Material

Day 1

Day 2

Poster Exhibition

Rapporteurs Summaries

Background Material

Press Release

Symposium Programme

2012 Press Conference
   Webcast

Global Scientific Strategy


Full Recommendations

Commentary

Policy Paper

Symposium Report

With the support of:

ANRS

NIH

Sidaction

TAG