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Abstract
Anorectal lesions in HIV+ outpatients of the infectious diseases´ clinic of the universitary hospital of Brasilia
M.R. Retamozo-Palacios1, J.B. Santos1, J.B. Souza2, P.G. Oliveira2
Background: Anorectal lesions (ARL) are common in HIV patients, but there aren’t especific informations about the prevalence of these lesions, frequently observed in the evolution of HIV infection. Aproximately 35% of the HIV+ population will develop anorectal symptoms during the Retroviral infection. Some risk factors were identificated for developing anal patology: anal intercourse, use of IV drugs and chronic diarrhoea. Our objectives were: to measure the prevalence of ARL in HIV+ outpatients of infectious diseases’ clinic of University Hospital from Brasilia (HUB); to identify the most frequent ARL; to verify the correlation between ARL and homosexuality in men; and to observe the factors associated with ARL in HIV+ patients.
Methods: This was a cross-sectional study, and was developed in the clinics of Infectious Diseases and Coloproctology of the HUB, from June to December of 2004. One hundred HIV-positive patients were submitted to proctologic exam after a free consent term, at the Coloproctology clinic. When lesions identified, they were submitted to flexible rectal-sigmoidoscopy and/or video-colonoscopy as diagnostic and/or therapeutic procedures.
Results: The prevalence of pathologic ARL in HIV-positive patients was 56%, and the most frequent were: warts (20%) and fissures (11%). Anal tags (51%) were the most prevalent non-pathologic ARL. The most frequent symptom was anal pruritus (16%). and anal warts (23%) were the most frequent detected sign. Important statistically significant correlations were: Viral Load levels upon 5 log with a high rate of external hemorrhoid components; homosexuality in men who have sex with men with active and passive roles, tabagism, use of HAART including the protease inhibitor LPV/r, hypercholesterolemia and hypertrigliceridemy, with a high rate of anal warts. There wasn’t correlation between CD4+ counting and ARL.
Conclusions: This study suggests that the proctologic exam should be part of the surveillance routine of HIV-positive patients, especially in those with risk factors for developing anorectal pathologic lesions.
AIDS 2006 - XVI International AIDS Conference
Abstract no.
CDC0187
Suggested Citation
"M.R.Retamozo-Palacios, et al.
Anorectal lesions in HIV+ outpatients of the infectious diseases´ clinic of the universitary hospital of Brasilia.
:
AIDS 2006 - XVI International AIDS Conference:
Abstract no.
CDC0187"
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