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Abstract



What do US Census Bureau databases reveal about the history of the HIV/AIDS outbreak in Brazil?

Shandera W.X.1

Introduction: Brazil is known for its control of AIDS despite restricted resources. We analyzed the history of AIDS in Brazil among different at-risk populations and geographic areas, to determine parameters associated with successful containment.
Methods: The US Bureau of the Census databases (2004 version) for Brazil were organized by risk factor and geographic area and collated using regression techniques with STATA. Linear and best-fit nonlinear curves were applied to the data. Only cities with > 10 studies were included in comparative geographic analyses.
Results: Among 1059 studies, 457 (43%) were conducted in Sao Paulo and/or Rio de Janeiro. The median (mean) seroprevalence for all studies was 4.2% (mean 13.5%), changing change from 1.8% (11.2%) in 1986 (32 studies) to 3.7% (9.1%) in 2001 (45 studies). The highest prevalences were 1991 (median 20.6%, mean 25.6%, 73 studies). The risk factor groups with highest prevalence historically were hemophiliacs (54,7%, 48%, median, mean prevalence), followed by transvestites (49%, 53.1%), drug users (38.3%, 37.8%), and sex partners of the infected (33.5%, 28.2%). Geographic areas with highest mean and median HIV prevalence were reported from Santos (10%, 26.6%). Linear slopes showed declining values for hemophiliacs/transfusion recipients (-4.15), infants in vertical transmission studies (-3.57), drug users (-1.23), street youth/gang members (-1.94), suspect HIV-infected populations (-1.82), hospitalized patients (-0.83), and prisoners (-0.78). Less significant changes were seen among partners of the HIV-infected (-0.15) and commercial sex workers (-0.08), commercial sex workers (-0.03) and patients in STD clinics (-0.16), and gay men (-0.01). An increase in prevalence was seen among tuberculosis patients (+3.25).
Conclusions: The highest HIV seroprevalence values for Brazil were registered in 1991. Despite limitations of seroprevalence data, these findings suggest significant improvement in prevalence rates among groups such as street youth, but are a reminder of the potent interactions between TB and HIV.





The 3rd IAS Conference on HIV Pathogenesis and Treatment
Abstract no. MoPe10.1P01


Suggested Citation
" Shandera W.X. What do US Census Bureau databases reveal about the history of the HIV/AIDS outbreak in Brazil?. Poster Exhibition: The 3rd IAS Conference on HIV Pathogenesis and Treatment: Abstract no. MoPe10.1P01"