HIV disclosure in HIV positive Thai children
Objectives: To determine the prevalence of children who were informed of their HIV status and the correlations between HIV disclosure, and immunological, virological outcomes and ARV adherence.
Methods: A cross-sectional study conducted in Bangkok from August 2006 to January 2007. Eighty seven primary caregivers of children with HIV aged six year and older were interviewed to assess the child disclosure status. Medical records were reviewed for demographic data and pill count was done to calculate adherence. Correlation was analyzed by SPSS program.
Results: Eighty seven children were included. The median age was 10.0 years (IQR 8 to 13, range 6 to 17). 44 (50.6%) was boys. Almost children were mother to child transmission. 75 (86.2%) children were on ARV. % CDC status N:A:B:C was 5:47:26:22. Median CD4 was24% (IQR 17 to 28) and median viral load log10 was 1.7 (1.7 to 3.2). 16 (18.4%) of children were informed of their HIV status. The median age of children who were informed and uninformed was 14 and 9 years respectively. The % of informed children was different between age groups: 0, 18.8 and 62.5 for 6-9, 10-13, and 14-17 years respectively. The % of informed children did not differ in those who were on or off ARV. There was no significant correlation between disclosure status, and CDC class, CD4%, CD4 count and viral load log10. Of the ARV-treated group, adherence by pill count was not different among the informed and uninformed groups.
Conclusions: 18.4 % of children were informed HIV status, most of whom were 14-17 years. There was no significant correlation between disclosure of HIV and HIV disease status. Knowledge of HIV diagnosis did not impact adherence to ARV. There is a need for further studies, especially in adolescents group, to determine the impact of disclosure on adherence and HIV treatment outcome.
4th IAS Conference on HIV Pathogenesis, Treatment and Prevention
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HIV disclosure in HIV positive Thai children.
4th IAS Conference on HIV Pathogenesis, Treatment and Prevention: