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Abstract
HIV–1 acquisition and disease progression are associated with decreased high–risk sexual behaviour among Ugandan female sex worker
Nalutaaya C.1
Objectives: To test the hypothesis that HIV – 1 seroconversion and disease progression are associated with changes in risk behaviors, using data from a cohort of Ugandan female sex workers (FSWS).
Methods: HIV–1 seronenegative FSWS were enrolled in a prospective study of risk factors for HIV–1 acquisition At monthly visits, standardized interviews were conducted to access sexual risk behavior and HIV–1 serologic testing was performed. Seroconversions were invited to continue with follow – up. Between 1993 and 2004 (when antiretroviral therapy was introduced in the cohort), 265 women seroconverted for HIV 1 (incidence 7.7/100 person – years) and were include in this analysis.
Results: unprotected intercourse was reported at 5462037 (27%) pre – seroconversion visits versus 557/ 3732 (15%) post – seroconversion visits (p < 0.001). these findings remained significant after adjustment for potential confounding factors (adjusted odds ration (AOR) 0.69,95% confidence interval (c1), 0.55 –86) compared with HIV–1 seronegative women, there was a progressive stepwise decrease in unprotected intercourse among HIV-1 seropositive women with CD4 cell counts > 500 (AOR, 0.93, 95% CI, 0.62 – 1.39 200 – 499 ( AOR, 0.58, 95% C1,0.41 – 0.82) and < 200 cells or, 0.45; 95% C1, 0.25 – 0.82). Decreases in unprotected i9ntercouse reflected increases in both abstinence and 100% condom use. Women also reported fewer partners and fewer episodes of intercourse after HIV – 1 seroconver on.
Conclusions: HIV – 1 seroconversion and disease progression were associated with decreases in sexual risk behavior among Ugandans FSWS.
4th IAS Conference on HIV Pathogenesis, Treatment and Prevention
Abstract no.
CDA038
Suggested Citation
" Nalutaaya C.
HIV–1 acquisition and disease progression are associated with decreased high–risk sexual behaviour among Ugandan female sex worker.
:
4th IAS Conference on HIV Pathogenesis, Treatment and Prevention:
Abstract no.
CDA038"
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