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Abstract
Incidence of HIV and Candida albicans vulvagainitis infection amongst febrile pregnant women
Enya V.N.1, Idigbe O.2, Agomo P.U.1, Idika N.3, Oparaugo C.T.2, Onyewuche J.2, Onwujekwe D.4
Objectives: In Nigeria fever is usually considered as malaria. This study was carried out inorder to determine the incidence of HIV and Candida albicans infections among malaria negative pregnant women.
Methods: The study period was between 1997 and 2003 approved by Lagos State Hospital Management Board Ethics Committee. A total of 240 participants: 140 febrile pregnant women and 100 non pregnant apparently healthy women(control group) were enrolled following their informed consent. Finger prock blood specimens and ICT rapid diagnostic test were used to exclude positive malaria cases. Blood specimen(5mls) and high vaginal swab(HVS) were aseptically collected from each participant by the attending clinician and transported immediately to NIMR for processing. The HIV test was carried out using two enzyme-linked immunosorbent assays: Genic 11 HIV-1/HIV-2 and Capillus(R) HIV-1/HIV-2. HIV 1, 2 positive sera were discriminated using the pepti-law-1-2 test kit. Statistical analysis was done using SpSS statistics.
Results: Seven percent of the test group was positive for HIV-1, and 2.1% were HIV-2 positive. All members of the control group were HIV negative. Vaginal candidaisis was demonstrated in 40.0% of the test group and 11.0% of the control group. More than eghy-eight percent of the 153 Candida species isolated were Candida albicabs and 11.9% were other species of Candida.Over eight-one percent of the Candida albicans were isolated from pregnant women and 18.6% came from the control group. The pregnant women who were HIV-1 positive also showed positive for Candida albicans. ten percent of the HIV-1 positive casess indicated positive for Trichomonas vaginalis infection, and 4% of the control group were only positive for Trichomonas vaginalis.
Conclusions: This study indicated the need to test for HIV, Candida albicans, and malaria infections among febrile antenatal patients in Nigeria. This will to enhance early dictation and treatment of HIV infection in pregnant women rewducing mother to child HIV transmission.
4th IAS Conference on HIV Pathogenesis, Treatment and Prevention
Abstract no.
CDA013
Suggested Citation
"EnyaV.N., et al.
Incidence of HIV and Candida albicans vulvagainitis infection amongst febrile pregnant women.
:
4th IAS Conference on HIV Pathogenesis, Treatment and Prevention:
Abstract no.
CDA013"
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