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Abstract
HIV/AIDS for vertical transmission. 20 years of experience in Cuba
Gonzalez-Nuñez I.1, Diaz-Jidy M.1, Perez Avila J.1
Objective: A controlled program is established in primary health care in Cuba, since 1986 with the object to reduce vertical transmission.
Methods: Each HIV+ pregnant woman who decides to keep her pregnant receive ZDV or TARGA according to their immunologic state, from week 14 to 38 when Caesarean operation is carried out. No maternal nursing. During his first 6 weeks, the child receives AZT (2mg/Kg/dose) every 6 hours. Evolution of these children is made in IPK external office, where they are studied to determine HIV infection.
Infected children are treated with antiretrovirals, according to opportunistic diseases, CD4 and viral load. Quantification of CD4 is determined by flow cytometry, using a FACScan cytometer from Becton Dickinson. Quantification of viral RNA levels was made through the Nuclisens system from Biomerieux.
Results: A total of 1589 seropositive women have been reported since January 1, 1986 to December 31, 2006 (19, 6%) of all the seropositive cases of the country (1589/ 8087), 248 (15,6%) have given birth a total of 265 children (15 women have delivered twice and 2 have twins); 29 of 265 are HIV+ (10,9%), 27 classified as AIDS (27/29=93,1%), 18 are under treatment with HAART; 2 are asymptomatic and 9 (9/29=31,0%) died. No infection was demonstrated in 170 children by PCR and Western Blot (170/265=64,1%) and 65 (65/265=24,5%) are still under study.
Conclusion: The Program and Prevention and Control of Vertical transmission is effective as the amount of infected children is low similar to that developed country.
4th IAS Conference on HIV Pathogenesis, Treatment and Prevention
Abstract no.
CDC095
Suggested Citation
"Gonzalez-NuñezI., et al.
HIV/AIDS for vertical transmission. 20 years of experience in Cuba.
:
4th IAS Conference on HIV Pathogenesis, Treatment and Prevention:
Abstract no.
CDC095"
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