|
|
Abstract
Resolution of anaemia with use of HAART among HIV-1 infected patients in a resource limited setting like Northern Ngeria
James A.1, Imade G.1, Bandung B.P.1, Sambo N.1, Nimzing L.1, Idoko J.1, Kanki P.2
Objectives: Anaemia has been shown to be significant predictor of progression to AIDS and it is associated with an increased risk of death in patients with HIV.However,in developing countries it is worst due to a high prevalence of background anaemia as a result of nutritional deficiencies,intestinal parasites,tuberculosis and other opportunistic infections.Basically,the objective of this study is to assess the influence of highly active antiretroviral therapy(HAART) on the rate of anaemia among HIV-1 infected individuals in North central Nigeria.
Methods: This study was carried out in APIN Laboratory,Jos University Teaching Hospital from 2004-2006.A total of 12,317 HIV patients confirmed by western blot technique who met the inclusion criteria for HAART were assessed.A baseline packed cells volume(PCV) measured within 12 weeks prior to HAART initiation was compared with PCV measurements between 12-52 weeks after commencement of HAART.Anaemia was classified by W.H.O.criteria.This retrospective analsis was performed using SPSS version 12.
Results: 45.4% of patients were not anaemic at HAART initiation,this increased significantly to 96.7% during follow-up visits.Prior to HAART initiation,median baeline CD4+ counts was 156cells/ul and 260cells/ul after initiation.
Conclusions: This finding further justifies the need for greater access to HAART in developing countries,especially since this life-saving therapy still remains unavailable to the majority of people who need it in resource limited settings.
4th IAS Conference on HIV Pathogenesis, Treatment and Prevention
Abstract no.
CDB068
Suggested Citation
"JamesA., et al.
Resolution of anaemia with use of HAART among HIV-1 infected patients in a resource limited setting like Northern Ngeria.
:
4th IAS Conference on HIV Pathogenesis, Treatment and Prevention:
Abstract no.
CDB068"
|
|
|