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Abstract
Nutrition in HIV Transmission and Management
S M Samali Matovu, K F M Kasozi Francis, O M Okia Martin, M J Mayanja James
The AIDS Support Organisation (TAS0)(U)Ltd , Kampala, Uganda
ISSUE: Poor nutritional status of many HIV positive individuals has been associated wirh faster disease progression among HIV positive women and increases risk of HIV transmission from mother to infant.
PROJECT: In 1999 The AIDS Support Organisation (TASO) with Medicines du monde carried out a double blinded, placeblo contralled trial among HIV positive pregnant women attending our clinic. 380 women were randomly assigned in a two by two group design to recieve a daily oral dose of one of four regimes right from enrollment until the end of the study; vitamin A alone, multivitamins excluding vitamin A multivitamins including vitamin A or placebo. Women between 12 and 27 weeks of gestation were legible at randomisation.
RESULTS: Multivitamins but not vitamin A resulted in large and significant reductions in the risks of feutal deaths, low birth weight, premature births and improvements in CD4 and CD8 cell counts of HIV positive mothers.
CONCLUSION: Mechanism of action of nutritional supplements in HIV infection need to be taken into account for proper management of HIV especially among HIV positive expectant mothers. Results from this study show that nutritional supplements to HIV pregnant women greatly reduce mother to child transmission of HIV and improves CD4 and CD8 cell counts of mother. There is need for more studies regarding effect of micro-nutrients to HIV positive individuals.
The XIV International AIDS Conference
Abstract no.
B10485
Suggested Citation
"S M Samali Matovu, et al.
Nutrition in HIV Transmission and Management.
Print Only:
The XIV International AIDS Conference:
Abstract no.
B10485"
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